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Method to identify undetected drug suicides wins top NIDA Addiction Science Award



A project that identified and tested a bioinformatics program that can help identify underreported suicides linked to drug overdoses was awarded the first-place distinction at the 2018 Intel International Science and Engineering Fair (ISEF)—the world’s largest science competition for high school…



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FDA approves first medication to reduce opioid withdrawal symptoms



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The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, is pleased to announce that lofexidine, the first medication for use in reducing symptoms associated with opioid withdrawal in adults, has been approved by the U.S. Food and…



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Study upends conventional view of opioid mechanism of action



​Fluorescence micrograph of a neuronal cell body showing the location of opioid receptor activation detected by the new biosensor immediately before (left panel) and 20 seconds after (right panel) application of morphine. Arrow points to the Golgi apparatus, a location within the interior of the…



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Nearly half of opioid-related overdose deaths involve fentanyl



An analysis of opioid-related overdose deaths found that synthetic opioids, such as illicit fentanyl, have surpassed prescription opioids as the most common drug involved in overdose deaths in the U.S. A research letter published in the Journal of the American Medical Association (JAMA) concluded…



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Dr. Kurt Rasmussen to lead NIDA’s therapeutics and medical consequences division



Dr. Kurt Rasmussen

The National Institute on Drug Abuse (NIDA), a component of the National Institutes of Health, welcomed Dr. Kurt Rasmussen today as the Director of the Division of Therapeutics and Medical Consequences (DTMC). Dr. Rasmussen’s career spans more than 30 years of research and…



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Understanding the Neuroscience of Addiction: what it means for prevention and treatment



Advances in the understanding of brain development, as well as the role that genes and environment play in addiction, are the focus of a review article published today in The American Journal of Psychiatry. The authors discuss how more than three decades of research in genetics and neuroscience…



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Five million American adults misusing prescription stimulants



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Scientists at the U.S. Department of Health and Human Services have completed the first comprehensive analysis of the prevalence of prescription stimulant use, misuse, use disorders, and motivations for misuse in the U.S. adult population. Looking at annual averages,…



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Study changes long-held concepts of cell decoding



Scientists at the National Institute on Drug Abuse (NIDA) Intramural Research Program (IRP) have uncovered evidence that shows a more complex and elaborate role for the body’s hard-working G protein-coupled receptors (GPCRs) than previously thought, suggesting a conceptual advance in the fields of…



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E-cigarette ads associated with cigarette smoking initiation among youth



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A scientific study finds that receptivity to e-cigarette advertising increases the likelihood of trying conventional cigarettes one year later. The research was funded by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, and the Center…



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Non-psychoactive cannabinoid may enable drug addiction recovery



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An animal study finds that cannabidiol (CBD), a non-psychoactive chemical found in marijuana, may help reduce the risk of drug and alcohol relapse. The research, conducted by the Scripps Research Institute, was funded by the National Institute on Drug Abuse and the…



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NIDA's 2018 Avant-Garde awards highlight immune response and killer cells



With diverse proposals focused on everything from natural killer cells to therapeutic vaccines to treat HIV, three recipients have been selected for the 2018 Avant-Garde Award for HIV/AIDS Research from the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health. The…



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Pain relief without risk of addiction or overdose?



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New preclinical NIDA-funded research shows that a new compound, BU08028, acts on opioid and non-opioid brain receptors to relieve pain without harmful side effects. In the study, primates experienced pain relief but did not become dependent upon BU08028, and in fact,…



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NIH Big Data to Knowledge Initiative (BD2K) – New Funding Announcements



The NIH Big Data to Knowledge initiative (BD2K, https://datascience.nih.gov/bd2k) announces the release of two new RFAs for training in biomedical big data science:

RFA-MD-16-002 NIH Big Data to Knowledge (BD2K) Enhancing Diversity in Biomedical Data Science (R25)
RFA-ES-16-011 BD2K Research…



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Recruitment begins for landmark study of adolescent brain development



Recruitment for the Adolescent Brain Cognitive Development (ABCD) study, the largest long-term study of brain development and child health in the United States, began today. The landmark study by the National Institutes of Health will follow the biological and behavioral development of more than 10…



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Buprenorphine Prescribers Treat Below Current Patient Limits



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A new NIDA-funded study analysis found that the monthly numbers of opioid use disorder patients treated by buprenorphine prescribers were significantly below current limits, suggesting that barriers exist to securing treatment.

Buprenorphine, a medication effective in…



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Multi agency funding announcement to assist with opioid crisis in rural U.S. regions



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A new federal funding opportunity was announced today to help find solutions to the opioid use and overdose crisis in the nation’s rural regions. It includes a focus on coal-impacted counties within Appalachia, as well as rural communities in other parts of the…



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Structure of primary cannabinoid receptor is revealed



New research is providing a more detailed view into the structure of the human cannabinoid (CB1) receptor. These findings provide key insights into how natural and synthetic cannabinoids including tetrahydrocannabinol (THC)—a primary chemical in marijuana—bind at the CB1 receptor to produce their…



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NIDA-NIAAA Mini-Convention: Frontiers in Addiction Research



Relapse and Recovery: from Mechanistic Understanding to Translational Research

Society for Neuroscience satellite meeting explores notable studies in drug and alcohol research, in areas ranging from molecular mechanisms to treatment strategies

What: The National Institute on Drug Abuse (NIDA),…



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Registration opens for Drugs & Alcohol Chat Day



High schools can now register for the 10th annual Drugs & Alcohol Chat Day, a web chat to be held on January 26, during National Drug & Alcohol Facts WeekSM, which runs from January 23 – 29, 2017. Registrations are taken on a first–come, first-served basis and are limited to about 100…



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National Institute on Drug Abuse to hold teleconference discussing key findings of 2016 Monitoring the Future Survey on teen drug use



The National Institute on Drug Abuse (NIDA) will hold a teleconference on Tuesday, December 13, to discuss the results of the 2016 Monitoring the Future (MTF) survey. The survey, conducted earlier this year by scientists at the University of Michigan, tracks annual drug use and attitudes among…



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Teen substance use shows promising decline



The 2016 Monitoring the Future (MTF) annual survey results released today from the National Institutes of Health (NIH) reflect changing teen behaviors and choices in a social media-infused world. The results show a continued long-term decline in the use of many illicit substances, including…



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Preoccupation with muscle mass may spur steroid use among non-athlete men



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A new viewpoint written by scientists from the National Institute on Drug Abuse (NIDA) and Harvard Medical School describes that a growing number of young, non-athlete men are using androgenic-anabolic steroids (AAS) and other appearance and performance…



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Journal issue addresses nonmedical use of prescription drugs



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A special issue of the journal Addictive Behaviors features more than a dozen articles related to understanding and addressing the serious public health issues related to the nonmedical use of prescription drugs. Many articles are funded by the National Institute…



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New analysis highlights patterns of adult medical marijuana use



An analysis of medical marijuana use among adults in the United States indicates that more than 21 percent of medical marijuana users reside in states that have not legalized its use; suggesting that physicians might be recommending medical marijuana regardless of legalization in their respective…



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Study finds one in four high school e-cigarette users have tried “dripping”



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A study of high school students found that one in four teens reported using e-cigarettes for “dripping,” a practice in which users produce and inhale vapors by placing drops of e-liquids directly onto heated atomizer coils. In a survey of 1,080 Connecticut high school…



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Opioids are driving increase in cocaine overdose deaths



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An examination of national trend data shows that heroin and synthetic opioids are driving a recent increase in cocaine-related overdose deaths. The assessment was conducted by scientists at the National Institute on Drug Abuse (NIDA), the National Center for Injury…



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New resources available for criminal justice and drug treatment counselors



The National Institute on Drug Abuse (NIDA) has created several new resources for those who work within the criminal justice system and other environments where people in recovery are ready to return to their lives outside of a structured setting.

The new materials include:

Drugs & the Brain…



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NIDA announces recipients of 2017 Avant-Garde Awards for HIV/AIDS research



The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, today announced that three scientists have been selected to receive the 2017 Avant-Garde Award for HIV/AIDS Research. The winning proposals focus on a variety of novel approaches, including: improving HIV…



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Dr. Rita Valentino to lead NIDA’s neuroscience and behavior division



Dr. Rita Valentino

The National Institute on Drug Abuse (NIDA) at the National Institutes of Health welcomed Dr. Rita Valentino today as the Director of the NIDA Division of Neuroscience and Behavior. Dr. Valentino’s career spans 26 years of academic, research, and leadership experience in…



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College students at increased risk for smoking marijuana



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An analysis of national survey data indicates that students attending college are at a significantly higher risk of beginning to use marijuana than those not enrolled in college, underscoring the need for improved prevention efforts. The research, conducted by…



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Illicit cannabis use and use disorders increase in states with medical marijuana laws



An analysis of national survey data indicates that laws legalizing medical marijuana use are associated with increases in illicit cannabis use and cannabis use disorders among adults. The research was funded by the National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse…



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Study shows buprenorphine more effective than morphine for treatment of opioid withdrawal in newborns



A newly published study showed that buprenorphine is more effective than morphine in treating withdrawal symptoms in newborns prenatally exposed to opioids, known as neonatal abstinence syndrome (NAS). Unlike morphine, buprenorphine did not affect breathing rates, although medications were…



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NIDA hosts sessions on pain at APA annual meeting



Dr. Nora Volkow to receive APA Special Presidential Commendation

To help address the ongoing prescription opioid overdose epidemic, the National Institute on Drug Abuse (NIDA) will host sessions on the management and treatment of pain as it relates to substance use disorders at the 2017 American…



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Epigenetics takes center stage with this year’s Addiction Science Awards 



A project applying the science of epigenetics to demonstrate the health dangers of hookah smoke won a first-place Addiction Science Award at the 2017 Intel International Science and Engineering Fair (ISEF)—the world’s largest science competition for high school students. The awards are coordinated…



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Long-term anabolic steroid use linked to damage to heart and arteries



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New research funded by the National Institute on Drug Abuse (NIDA) found that long-term exposure to anabolic-androgenic steroids may be associated with substantial impairment of the heart, including a reduction in pumping performance and damage to the…



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Intensive intervention increases clinical adherence to opioid prescribing guidelines in chronic care



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There is much discussion on the safety and effectiveness of prescribing opioids for chronic pain patients. While the Centers for Disease Control and Prevention has issued clinical guidelines for chronic opioid therapy, these guidelines are not followed by many…



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Pain relief most reported reason for misuse of opioid pain relievers



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More than one third of adults nationwide reported prescription opioid use in 2015, with substantial numbers reporting misuse and use disorders, according to a report compiled to estimate the prevalence of, and explore the motivations for, opioid use and misuse. The data…



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Energy drinks and risk to future substance use



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New research suggests that college students who regularly consume energy drinks are at a greater risk for future alcohol use disorder, cocaine use or nonmedical use (misuse) of prescription stimulants. The research was funded by the National Institute on Drug Abuse (NIDA…



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Grants awarded to address opioid crisis in rural regions



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To address the opioid crisis in rural U.S. regions, the National Institute on Drug Abuse (NIDA), in partnership with several other federal agencies, have issued nine grants to help communities develop comprehensive approaches to prevent and treat consequences of…



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Event registration opens for National Drug & Alcohol Facts Week®



The National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA) announced that event registration begins today for the next National Drug & Alcohol Facts Week® (NDAFW), to be held Jan. 22-28, 2018. NDAFW is an annual, week-long series of…



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Women who inject drugs may be at greater risk of HCV than men



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There is a clear body of research assessing sex and gender differences in risk behaviors among people who inject drugs, however little or no research has investigated sex differences in hepatitis C (HCV) susceptibility. A newly published analysis examining data from…



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Collaborative care shows promise for opioid and alcohol use disorders



A NIDA-funded randomized clinical trial found that primary care patients with opioid and alcohol use disorders (OAUD) who were offered a collaborative care intervention were more likely to receive evidence-based treatment and refrain from using opioids and alcohol six months later, compared to…



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Young adults’ daily use of marijuana a concern



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The National Institute on Drug Abuse (NIDA) announced that the latest Monitoring the Future (MTF) national survey results of drug use among full-time college students and their non-college peers are now available online, highlighting that daily marijuana use is at the highest…



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Marijuana use is associated with an increased risk of prescription opioid misuse and use disorders



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New research suggests that marijuana users may be more likely than nonusers to misuse prescription opioids and develop prescription opioid use disorder. The study was conducted by researchers at the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health,…



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Study highlights unmet treatment needs among adults with mental health and substance use disorders



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Despite current treatment guidelines, fewer than 10 percent of adults with co-occurring mental health and substance use disorders receive treatment for both disorders, and more than 50 percent do not receive treatment for either disorder. The findings highlight a large…



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Study identifies a brain pathway involved in drug relapse after cessation of contingency management



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A team of researchers at the National Institute on Drug Abuse (NIDA) has identified what may be the crucial brain circuit involved in relapse to drug use when an effective behavioral treatment for drug addiction, known as contingency management, is discontinued….



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NIDA launches two adolescent substance use screening tools



The National Institute on Drug Abuse (NIDA) has launched two evidenced-based online screening tools that providers can use to assess substance use disorder risk among adolescents 12-17 years old. These tools can be self-administered or completed by clinicians in less than two minutes.  They are…



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NIDA-NIAAA Mini-Convention: Frontiers in Addiction Research: The Science of Astrocytes, Stress Response, and Translational Research



What: The National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health, will host a one-day mini convention, a satellite event of the 2017 Society of Neuroscience annual meeting. NIDA and NIAAA grantees will…



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Opioid treatment drugs have similar outcomes once patients initiate treatment



A study comparing the effectiveness of two pharmacologically distinct medications used to treat opioid use disorder – a buprenorphine/naloxone combination and an extended release naltrexone formulation – shows similar outcomes once medication treatment is initiated. Among active opioid users,…



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Separating side effects could hold key for safer opioids



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Opioid pain relievers can be extremely effective in relieving pain, but can carry a high risk of addiction and ultimately overdose when breathing is suppressed and stops. Scientists have discovered a way to separate these two effects — pain relief and breathing –…



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