Category: DrugAbuse.Gov

17
Nov
2020
Posted in DrugAbuse.Gov

Intervention increases use of Medication for both HIV/AIDS and Substance Use Disorders

A vanguard study with people who inject drugs provides evidence that a specific flexible, scalable intervention increases reported use of both antiretroviral therapy for HIV/AIDS…

17
Nov
2020
Posted in DrugAbuse.Gov

Novel Dopamine D3 Receptor Antagonist Reduces Opioid Addiction-Like Behaviors in Rats

The dopamine D3 receptor antagonist VK4-116 reduced oxycodone self-administration in rats, as well as drug-seeking behaviors after oxycodone reinstatement following withdrawal. VK4-116 did not interfere…

17
Nov
2020
Posted in DrugAbuse.Gov

A New Era at NIDA Notes

As we enter a new year, we would like to honor and thank NIDA Notes Editor David Anderson, who recently retired after 20 years at…

17
Nov
2020
Posted in DrugAbuse.Gov

Hearing on Cannabis Policies for the New Decade

Chairwoman Eshoo, Ranking Member Burgess, and members of the Subcommittee, thank you for inviting the National Institute on Drug Abuse (NIDA), a component of the…

17
Nov
2020
Posted in DrugAbuse.Gov

AOUD Treatment in Primary Care Settings—Is it Feasible?

Treatment for alcohol and opioid use disorders (AOUD) is feasible in primary care settings, but ongoing funding to support organizational capacity is critical for sustaining…

17
Nov
2020
Posted in DrugAbuse.Gov

Coaxing the brain to pay attention to healthier choices

Neuroscience research from NIDA’s Intramural Research Program suggests that cortical mechanisms, especially in the orbitofrontal cortex, are likely involved in attentional bias to cocaine associated…

17
Nov
2020
Posted in DrugAbuse.Gov

Part 1: Immunotherapies—A New Tool To Treat Methamphetamine Addiction?

Researchers have created a monoclonal antibody (mAb) that is intended to interact with methamphetamine and decrease its ability to enter the brain. Source link

17
Nov
2020
Posted in DrugAbuse.Gov

Part 2: Immunotherapies—A New Tool To Treat Methamphetamine Addiction?

Researchers move their monoclonal antibody (mAb) into clinical trials to see if it can be an effective treatment for methamphetamine use. Source link

17
Nov
2020
Posted in DrugAbuse.Gov

Many teens who overdose on opioids do not get effective follow-up

An analysis of Medicaid records shows that less than one-third of youths treated for a nonfatal opioid overdose received timely follow-up treatment, and only 1…

17
Nov
2020
Posted in DrugAbuse.Gov

Antiretroviral Therapy Combined With CRISPR Gene Editing Can Eliminate HIV Infection in Mice

This study found that HIV-1 could be eliminated in mice using a combination of two antiviral technologies—long-acting viral reservoir—targeted antiretroviral therapy and CRISPR/Cas-9 gene editing….

17
Nov
2020
Posted in DrugAbuse.Gov

Babies exposed to HCV not adequately tested

NIDA-funded science has found that HCV exposed infants might not be commonly or adequately tested. Source link

17
Nov
2020
Posted in DrugAbuse.Gov

NIDA scientists: Blocking adenosine receptors should counteract adverse effects of cannabinoids

Computational modeling by NIDA scientists suggests the possible use of adenosine A2A receptor antagonists to counteract the adverse effects of cannabinoids. Source link

17
Nov
2020
Posted in DrugAbuse.Gov

Study highlights effectiveness of methadone and buprenorphine

In a comparative effectiveness study of 6 approaches to treatment for opioid use disorders, only treatment with buprenorphine or methadone was associated with reduced risk…

17
Nov
2020
Posted in DrugAbuse.Gov

E-Cigarette Characteristics May Influence Use and Are Potential Targets for Regulatory Policy

People’s decisions to use e-cigarettes, as well as perceptions about associated risks, are influenced by the e-cigarettes’ nicotine levels and available flavors. The influence of…

17
Nov
2020
Posted in DrugAbuse.Gov

Serotonin Receptor Agonist Lorcaserin Reduces Relapse to Drug Use in Monkeys

The serotonin 2C receptor agonist lorcaserin reduced reinstatement of drug-seeking behavior in response to heroin or cocaine in a nonhuman primate model of relapse. Source…

17
Nov
2020
Posted in DrugAbuse.Gov

COVID-19 is an Emerging, Rapidly Evolving Situation

Links to the latest resources on COVID-19 Source link

17
Nov
2020
Posted in DrugAbuse.Gov

National Drug and Alcohol Facts Week® celebrates 10 years

NDAFW is an annual, week-long observance in which local educational events link teens with science-based facts about drugs and alcohol through live and online activities…

17
Nov
2020
Posted in DrugAbuse.Gov

New biological clues linking social connectedness to reduced drug craving and relapse

This rodent study offers the first mechanistic explanation for the protective effect of social interaction related to incubation of craving, showing for the first time…

17
Nov
2020
Posted in DrugAbuse.Gov

Stronger Brain Circuit Connectivity May Predict Nicotine Dependence Severity

The degree of connectivity of a neuronal network in the rat brain before nicotine exposure can help predict nicotine dependence severity after nicotine exposure as…

17
Nov
2020
Posted in DrugAbuse.Gov

Dopamine Neurons Signal Rich Information About Unexpected Events

In this study, both rats and humans learned to predict differently flavored rewards in parallel choice tasks, showing that dopamine neurons are carrying much more…

17
Nov
2020
Posted in DrugAbuse.Gov

Many People Treated for Opioid Overdose in Emergency Departments Die Within 1 Year

About 1 in 20 patients treated for a nonfatal opioid overdose in an emergency department died within 1 year of their visit, many within 2…

17
Nov
2020
Posted in DrugAbuse.Gov

Stigma and addiction addressed in New England Journal of Medicine

In a perspective released today in The New England Journal of Medicine, NIDA Director Dr. Nora Volkow addresses how stigma against people who use drugs can sabotage…

17
Nov
2020
Posted in DrugAbuse.Gov

NIDA Director outlines potential risks to people who smoke and use drugs during COVID-19 pandemic

The precarious intersection of the COVID-19 national health emergency and the concurrent epidemic of drug overdose deaths is outlined in the Annals of Internal Medicine…

17
Nov
2020
Posted in DrugAbuse.Gov

Marijuana vaping and edible use increasing among high school seniors

A new analysis suggests that among adolescent marijuana users, smoking has become less prevalent, eclipsed by vaping and edibles. Source link

17
Nov
2020
Posted in DrugAbuse.Gov

Mu Opioid Receptors in One Brain Region Contribute to Naloxone Aversion

Mice genetically engineered to lack mu opioid receptors in the medial habenula were less sensitive to the unpleasant effects of the opioid antagonist naloxone and…